Venting, Air and Gas Filtration

 

简介

颇尔 filters for pharmaceutical air and gas service are optimized for use in prefiltration of compressed or pressurized gases, and sterile air or gas filtration to completely remove particles, droplets, microorganisms like molds, yeasts or bacteria and even viruses and phages.These filters also find wide use in negative pressure applications such as sterile filtration of vacuum break lines on lyophilizers and autoclaves, and sterile and non-sterile venting of tanks and containers.颇尔 filters for air and gas service are available in a range of proprietary -manufactured hydrophobic filter media, including PTFE and PVDF as well as glass fiber, polypropylene, cellulose and porous stainless steel.颇尔 air and gas filters can be sized to meet a wide range of flow and pressure drop requirements, from sterile venting in the laboratory to small process flows in pilot operations, from compressed air flows in process scale operations to full scale air supply in large scale aerobic fermentations at ambient or elevated temperatures.

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Venting, Air & Gas Applications

应用Why filtration is importantHow 颇尔 Can Help
Sterile Venting of:Tanks, Vessels and Transport Containers, Autoclaves, Lyophilizers, Incubators, and Isolators 制药运营中的灌装和排水操作会引起空气进出容器。In most cases no airborne particles or microorganisms are allowed to enter critical product or water tanks. 颇尔 Emflon® PFR filters are hydrophobic sterile filters removing microorganisms, viruses and particles.They are integrity testable and validated, also for long-term use.For small scale applications that require SIP capability in a disposable capsule, the Novasip filter can be used.GMP compliant Pall Advanta® housings support high air flow rates for economic system design.
Sterile Filtration of Pressurized Air or Gas:Biotechnical Air Supply, Exhaust Air Filtration, Filling and Blow Fill Seal Operations, and Transport of Liquids Many pharmaceutical and biotechnological processes need pressurized air or gas as a basic requirement for optimized operation or cell growth.In most products and processes no particles or microorganisms are allowed to enter via air or gas supply lines whereas biohazardous organisms are not allowed to leave into the environment.
Sterile Filtration of High Flow Fermentor Air Supply 100 米3 或更大体积的大型发酵罐的运行需要极高流量的无菌空气以保证高效的细胞生长。Historically, large glass fiber towers or multiple narrow bore cartridges have been used. Wide bore Emflon® sterile filters provide flow rates of up to 5000 Nm3/h/cartridge (3000 SCFM/cartridge).小巧的系统尺寸、较低的成本和方便易用是这种过滤器的几大关键优势。过滤器可进行完整性检测,可确保以经济、安全和高效的方式取代填料塔和传统的多滤芯无菌空气过滤器。还可提供预过滤器以确保较长的使用寿命和低压降。
Venting and Sterile Filtration of Pressurized Air or Gas in Extreme Environments Some processes in the biopharmaceutical industry that needs sterile air filtration or venting operations are running at higher temperatures.如果标准材料与极端的环境条件无法兼容,则可能会影响到工艺安全性。 Special air filter elements like Emflon® CFR filters with improved material resistance are able to provide safety and long service lives in environments with higher temperatures or elevated oxidation stress.

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